Imipramine is primarily used for the treatment of depression and certain anxiety disorders, including acute post-traumatic stress reactions. A significant … See more

Combining it with alcohol consumption may cause more drowsiness, necessitating greater caution when drinking. It may be unsafe during pregnancy See more

These side effects can be contributed to the multiple receptors that imipramine targets such as serotonin, norepinephrine, dopamine, … See more

Like other tricyclic antidepressants, imipramine has many medication interactions. Many MAOIs have serious interactions with … See more

Pharmacodynamics
Imipramine affects numerous neurotransmitter systems known to be involved in the etiology of depression, anxiety, See more

Imipramine is a tricyclic compound, specifically a dibenzazepine, and possesses three rings fused together with a side chain attached in its chemical structure. Other … See more

The parent compound of imipramine, 10,11-dihydro-5H-dibenz[b,f]azepine (dibenzazepine), was first synthesized in 1899, but no pharmacological assessment of this compound or … See more